Craig Biggio got hit No. 2,993 in the fifth and scored on Hunter Pence's double, but an eight-run bottom of the fifth for the Rangers would chase Woody Williams and put the game out of reach for the Astros.
Sammy Sosa hit home run No. 601 to start an eight-run inning, which also featured home runs by Marlon Byrd and Brad Wilkerson. Sosa would cap off the inning with a two-run single to put the game out of reach. Kevin Millwood picked up the win.
The following are trademarks or service marks of Major League Baseball entities and may be used only with permission of Major League Baseball Properties, Inc. or the relevant Major League Baseball entity: Major League, Major League Baseball, MLB, the silhouetted batter logo, World Series, National League, American League, Division Series, League Championship Series, All-Star Game, and the names, nicknames, logos, uniform designs, color combinations, and slogans designating the Major League Baseball clubs and entities, and their respective mascots, events and exhibitions.